Replimune’s mission is to revolutionize cancer treatment with therapies designed to activate a powerful and durable full-body anti-tumor response, boldly transforming cancer care because patient’s lives depend on it. We imagine a world where cancer is a curable disease. 

 At Replimune, we live by our values: 

United: We Collaborate for a Common Goal. 

Audacious: We Are Bold and Innovative. 

Dedicated: We Give Our Full Commitment. 

Candid: We Are Honest With Each Other. 

People are at the center of everything we do, and when it comes to our employees, we make it personal.  With a deep sense of purpose, an innovative and collaborative culture, a competitive and forward-looking total rewards program, everyone at Replimune has a unique opportunity to contribute to the meaningful work we do which could impact the lives of patients.  

 Join us, as we reshape the future. 

Job Summary: 

The Senior Manager Facilities is responsible for routine management of the Facilities Department at the Framingham, MA manufacturing facility. The Facilities Department is responsible for ensuring all facility equipment and utilities are operating as required to support cGMP manufacturing, laboratory operations and administrative functions. The Senior Manager Facilities is responsible for ensuring all facilities related activities are executed per the required site SOPs, safe work practices and cGMP regulations. The Senior Manager Facilities is also responsible for supporting management in ensuring that the facility is operating per required environmental, health, safety and government regulations.

This position is based in our Framingham location and typically has a 5-day on-site expectation. 

Key responsibilities:

• Responsible for supervision and organization of the Facilities Department.
• Responsible for operation and maintenance of all utilities and systems required for support of cGMP manufacturing operation (HVAC, PW, PS, WFI, IT, etc.).
• Responsible for the operation and maintenance of all facility equipment and systems (HVAC, , security, stand-by generator, and base building systems).
• Coordinating routine and non-routine maintenance of all facility equipment, utilities and systems, including manufacturing and laboratory equipment.
• Management of CMMS for documentation and execution of maintenance and calibration for equipment and system assets.
• Ensuring all facilities related activities (maintenance, calibration, etc.) are documented per cGMP requirements.
• Coordinate, oversee and review work performed by outside contractors.
• Serve as Replimune’s liaison / contact with landlord, local authorities, etc.
• Responsible for management and operation of facility wastewater treatment and boiler operations per required licensing.
• Support EH&S / management to ensure proper disposal of all facility wastes, including both chemical and biological wastes, per all governmental regulations.
• Serve as Facility Emergency Coordinator / Safety Contact. Responsible for ensuring facilities are maintained in a safe manner and as key contact with employees and landlords regarding safety related items.
• Manage Facilities service contracts .

Other responsibilities

• Maintain equipment and facility to meet needs of support groups (Quality Control, Process Development, etc.).
• Manage facility construction / renovation projects or utility projects performed with external companies with review and approval of any project documentation and reports.
• Assist Engineering contractors with design, installation and modification of equipment / utilities
• Represent Facilities at inter-departmental meetings and interact with external vendors, as necessary.
• Provide Facilities support to Woburn office location as needed.
• Provide On-boarding/Off-boarding support to HR as needed.
• Other tasks as assigned.

Education:   

• A BA or BSc in Engineering, Science or a related discipline desired.

Required Experience: 

• Minimum 7 years’ experience managing daily facilities operations in a cGMP environment.
• Extensive experience with biopharmaceutical utility systems (HVAC, PW, PS, WFI) is a must.
• Training and/or field experience in building management systems, HVAC, refrigeration, plumbing and Health and Safety
• cGMP training and documentation experience
• Experience with biological and chemical waste management and Lockout/Tagout procedures
• Computer literacy (MS Word, MS Excel, Outlook, etc.)
• Ability to work well with others
• Excellent communication, organization and supervisory skills

About Replimune  

Replimune Group, Inc., headquartered in Woburn, MA, was founded in 2015 with the mission to transform cancer treatment by pioneering the development of a novel portfolio of oncolytic immunotherapies. Replimune’s proprietary RPx platform is based on a potent HSV-1 backbone intended to maximize immunogenic cell death and the induction of a systemic anti-tumor immune response. The RPx platform is designed to have a unique dual local and systemic activity consisting of direct selective virus-mediated killing of the tumor resulting in the release of tumor derived antigens and altering of the tumor microenvironment to ignite a strong and durable systemic response. The RPx product candidates are expected to be synergistic with most established and experimental cancer treatment modalities, leading to the versatility to be developed alone or combined with a variety of other treatment options. For more information, please visit www.replimune.com. 

We are an Equal Opportunity Employer. 

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